![Worldwide Coverage](https://ak-d.tripcdn.com/images/0wj5f12000aq250yp1F40.png?proc=resize/m_w,w_600,h_600,B0B3)
![One-stop Service Guarantee](https://ak-d.tripcdn.com/images/0wj4c12000aq250ld31BA.png?proc=resize/m_w,w_600,h_600,B0B3)
![Secure Payment](https://ak-d.tripcdn.com/images/0wj4r12000aq24uvwEB1C.png?proc=resize/m_w,w_600,h_600,B0B3)
Latest Flight Deals from Charleston to Des Moines
Book one-way or return flights from Charleston to Des Moines from as little as US$124. Choose from the popular airlines below and book your flight today!
- One way
- Round-trip
- CRW18:095h 54m1 stopDSM23:03Wed, Aug 14|Charleston - Des Moines|American AirlinesUS$124US$29857% OFF57% OFFUS$298US$124
- CRW07:004h 11m1 stopDSM10:11Wed, Aug 14|Charleston - Des Moines|United AirlinesUS$213US$29828% OFF28% OFFUS$298US$213
- CRW17:414h 48m1 stopDSM21:29Tue, Aug 13|Charleston - Des Moines|United AirlinesUS$241US$29819% OFF19% OFFUS$298US$241
- CRW06:005h 22m1 stopDSM10:22Wed, Aug 14|Charleston - Des Moines|Delta Air LinesUS$251US$251
- CRW13:003h 5mDirectDSM14:00Sat, Jul 6|Charleston - Des Moines|American AirlinesFind More FlightsFind More Flights
Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Searching for the best last minute flight from Charleston to Des Moines? Find one-way or return flights that are affordable and fit your itinerary.
Trip.com monitors the ticket fares of flights from Charleston to Des Moines. Stay updated on price trends and snag the best deals for your upcoming trip.
![](https://ak-d.tripcdn.com/images/0wj27120009rdg5nwB73D.png?proc=resize/m_w,w_600,h_600,B0B3)
View airlines operating flights from Charleston to Des Moines. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
![American Airlines](https://pic.tripcdn.com/airline_logo/3x/aa.png?proc=resize/m_w,w_600,h_600,B0B3)
![United Airlines](https://pic.tripcdn.com/airline_logo/3x/ua.png?proc=resize/m_w,w_600,h_600,B0B3)
![Delta Air Lines](https://pic.tripcdn.com/airline_logo/3x/dl.png?proc=resize/m_w,w_600,h_600,B0B3)
![airlines](https://pic.tripcdn.com/airline_logo/3x/mu.png_.webp?proc=resize/m_w,w_600,h_600,B0B3)
Find more flights and airlines
Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Charleston to Des Moines.
- CheapestCRW18:095h 54m1 transferDSM23:03Yeager Airport - Des Moines International AirportWed, Aug 14American AirlinesUS$124
- CRW18:095h 54m1 transferDSM23:03Yeager Airport - Des Moines International AirportWed, Aug 14American AirlinesUS$124Find More Flights
How do I find the cheapest flights?
How to find a cheap flight from Charleston to Des Moines
Cheapest nonstop flight price | $124 |
---|---|
Off-season for travel | August |
Peak season for travel | May |
Flight distance | 1,085.66km |
Popular airline | American Airlines |
Site Operator: Trip.com Travel Singapore Pte. Ltd.