Cusco to Santiago Flight Tickets, Fares starting @CAD 106

Flight FAQs

• Which airlines offer the cheapest flights from Cusco (CUZ) to Santiago (SCL)?

  Based on Trip.com data, JetSMART offers one-way fares as low as CAD 106 on Cheapest nonstop routes (e.g. CUZ to SCL on Fri, Dec 26), while JetSMART offers Cheapest nonstop round-trips from CAD 306 departing on Sun, Dec 21 and returning on Tue, Dec 23.

• Which airlines offer direct flights from Cusco to Santiago?

  At the moment, you can catch a direct flight from Cusco to Santiago with the following airlines, including: LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long is the flight from Cusco (CUZ) to Santiago (SCL)?

  It takes about 2 hours 20 minutes to fly from Cusco (CUZ) to Santiago (SCL).

• When is the best time to book flights from Cusco to Santiago?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Cusco to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Cusco to Santiago?

  Based on Trip.com data in the past 4 weeks, there is 7 flight per week flying from Cusco to Santiago. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/T/W/T/F/S -- LA2366 (09:32)

• How can I find the best deals on flights from Cusco to Santiago?

  To find best deals on flights from Cusco to Santiago, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Dec 26, with one-way flights priced at just CAD 106.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July.
  · Get exclusive promo codes for Trip.com app users.

• When is the best time to book a flight from Cusco to Santiago to get the best price?

  The cheapest months to fly from Cusco to Santiago is December, when demand for travel is lower.

• Which upcoming date is the cheapest for flights from Cusco to Santiago?

  After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Cusco to Santiago on December 12, 2025 with JetSMART, with prices starting at CAD 99.

• Which airports can I fly through when travelling to Santiago from Cusco?

  You can land at any one of the following hubs in Santiago, with Alejandro Velasco Astete International Airport to Arturo Merino Benitez International Airport (CUZ-SCL) is by far the most common option on this route: Arturo Merino Benitez International Airport (SCL).

• What is the time difference between Cusco and Santiago?

  The time difference between Santiago and Cusco is 1h.

• How can I change or cancel my flight ticket from Cusco to Santiago?

  Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.