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Flights from Memphis to Santiago

Find the cheapest flight options from Memphis to Santiago over the next three months. Book one-way tickets from US$520 and round-trip tickets from US$689.

      • MEM 15:03
        14h 47m
        1 stop
        SCL 08:50
        Memphis - Santiago | Wed, Jan 21 | United Airlines
        SCL 22:45
        26h 13m
        1 stop
        MEM 21:58
        Santiago - Memphis | Wed, Jan 28 | United Airlines
        US$689 US$4,006
        83% OFF
        83% OFF
        US$4,006 US$689
      • MEM 17:00
        12h 50m
        1 stop
        SCL 08:50
        Memphis - Santiago | Tue, Jan 20 | United Airlines
        SCL 22:45
        13h 28m
        1 stop
        MEM 09:13
        Santiago - Memphis | Tue, Jan 27 | United Airlines
        US$707 US$4,006
        82% OFF
        82% OFF
        US$4,006 US$707
      • MEM 17:00
        12h 50m
        1 stop
        SCL 08:50
        Memphis - Santiago | Wed, Jan 14 | United Airlines
        SCL 22:45
        13h 28m
        1 stop
        MEM 09:13
        Santiago - Memphis | Wed, Jan 21 | United Airlines
        US$842 US$4,006
        79% OFF
        79% OFF
        US$4,006 US$842
      • MEM 15:29
        14h 21m
        1 stop
        SCL 08:50
        Memphis - Santiago | Wed, Dec 24 | United Airlines
        SCL 22:45
        18h 6m
        1 stop
        MEM 13:51
        Santiago - Memphis | Sun, Dec 28 | United Airlines
        US$996
        75% OFF
        US$4,006 US$996
      • MEM 15:29
        14h 21m
        1 stop
        SCL 08:50
        Memphis - Santiago | Sun, Jan 4 | United Airlines
        SCL 22:45
        26h 13m
        1 stop
        MEM 21:58
        Santiago - Memphis | Sun, Jan 11 | United Airlines
        US$1,050
        74% OFF
        US$4,006 US$1,050
      • MEM 17:22
        11h 18m
        1 stop
        SCL 07:40
        Memphis - Santiago | Tue, Jan 20 | LATAM Airlines
        SCL 23:10
        20h 6m
        1 stop
        MEM 16:16
        Santiago - Memphis | Tue, Jan 27 | LATAM Airlines
        US$1,137
        72% OFF
        US$4,006 US$1,137
      • MEM 14:32
        14h 8m
        1 stop
        SCL 07:40
        Memphis - Santiago | Sun, Dec 14 | LATAM Airlines
        SCL 22:45
        13h 31m
        1 stop
        MEM 09:16
        Santiago - Memphis | Sun, Dec 21 | United Airlines
        US$1,188
        70% OFF
        US$4,006 US$1,188
      • MEM 17:00
        34h 10m
        1 stop
        SCL 06:10
        Memphis - Santiago | Sat, Dec 27 | Delta Air Lines
        SCL 23:10
        27h 8m
        1 stop
        MEM 23:18
        Santiago - Memphis | Sun, Jan 4 | Delta Air Lines
        US$2,073
        48% OFF
        US$4,006 US$2,073
      • MEM 15:29
        14h 21m
        1 stop
        SCL 08:50
        Memphis - Santiago | Sat, Dec 27 | United Airlines
        SCL 22:45
        13h 31m
        1 stop
        MEM 09:16
        Santiago - Memphis | Sun, Jan 4 | United Airlines
        US$2,925
        27% OFF
        US$4,006 US$2,925
      • MEM 13:00
        17h 25m
        1 stop
        SCL Invalid Date
        Memphis - Santiago | Sun, Dec 14 | Normal Airline
        SCL 15:00
        6h
        Direct
        MEM 16:00
        Santiago - Memphis | Tue, Dec 16 | Normal Airline
        Find More Flights
        Find More Flights
      • MEM 11:35
        18h 15m
        1 stop
        SCL 08:50
        Memphis - Santiago | Wed, Jan 7 | United Airlines
        US$520 US$780
        33% OFF
        33% OFF
        US$780 US$520
      • MEM 11:35
        18h 15m
        1 stop
        SCL 08:50
        Memphis - Santiago | Mon, Jan 12 | United Airlines
        US$521 US$780
        33% OFF
        33% OFF
        US$780 US$521
      • MEM 17:00
        12h 50m
        1 stop
        SCL 08:50
        Memphis - Santiago | Wed, Jan 21 | United Airlines
        US$536 US$780
        31% OFF
        31% OFF
        US$780 US$536
      • MEM 09:00
        20h 50m
        1 stop
        SCL 08:50
        Memphis - Santiago | Sun, Jan 4 | United Airlines
        US$538
        31% OFF
        US$780 US$538
      • MEM 19:15
        33h 25m
        1 stop
        SCL 07:40
        Memphis - Santiago | Sun, Feb 1 | Delta Air Lines
        US$543
        30% OFF
        US$780 US$543
      • MEM 09:00
        20h 50m
        1 stop
        SCL 08:50
        Memphis - Santiago | Wed, Dec 31 | United Airlines
        US$548
        30% OFF
        US$780 US$548
      • MEM 06:30
        23h 20m
        1 stop
        SCL 08:50
        Memphis - Santiago | Thu, Dec 25 | United Airlines
        US$553
        28% OFF
        US$780 US$553
      • MEM 11:35
        18h 15m
        1 stop
        SCL 08:50
        Memphis - Santiago | Fri, Jan 16 | United Airlines
        US$556
        28% OFF
        US$780 US$556
      • MEM 09:00
        20h 50m
        1 stop
        SCL 08:50
        Memphis - Santiago | Tue, Dec 23 | United Airlines
        US$559
        28% OFF
        US$780 US$559
      • MEM 11:35
        18h 15m
        1 stop
        SCL 08:50
        Memphis - Santiago | Sun, Feb 1 | United Airlines
        US$569
        27% OFF
        US$780 US$569
      • MEM 13:00
        17h 25m
        1 stop
        SCL Invalid Date
        Memphis - Santiago | Sun, Dec 14 | Normal Airline
        Find More Flights
        Find More Flights

Displayed flight fares from Memphis to Santiago are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Memphis to Santiago

The distance between Memphis and Santiago is 7,867.92km. Based on Trip.com's data, travel demand peaks in December. The off-season for travel is November.

Cheapest one-way flight priceUS$520
Cheapest return ticket priceUS$689
Off-season travel monthNovember
Peak season for travelDecember
Flight distance7,867.92km

Find the best time to fly from Memphis to Santiago

The cheapest time for Memphis to Santiago flights: Dec 21 to Dec 28 — one way flight prices from US$340.

Cheapest flights
From price
Search
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
  • 815
  • 1522

  • Mar

    221
Displayed fare trends are based on Trip.com's aggregated average of the lowest flight prices from Memphis to Santiago, calculated over the upcoming 10 weeks.

Flight FAQs

  • Which airlines offer the cheapest flights from Memphis (MEM) to Santiago (SCL)?

    Based on Trip.com data, United Airlines offers one-way fares as low as US$520 on Cheapest nonstop routes (e.g. MEM to SCL on Wed, Jan 7), while United Airlines offers Cheapest nonstop round-trips from US$689 departing on Wed, Jan 21 and returning on Wed, Jan 28.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Memphis to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Memphis to Santiago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Jan 7, with one-way flights priced at just US$520.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is United Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around December.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Memphis to Santiago is November, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Memphis to Santiago on December 24, 2025 with United Airlines, with prices starting at US$995.
  • The time difference between Santiago and Memphis is 2h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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