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Book flight tickets from Santiago to Lyon starting at US$428

Whether you’re going for a one-way or round-trip to Lyon, we’ve got you covered! Check out these different flight options from Santiago below.

  • One way
  • Round-trip
      • SCL21:05
        19h 15m
        1 stop
        LYS20:20
        Mon, Nov 18|Santiago - Lyon|LATAM Airlines
        US$428US$532
        20% OFF
        20% OFF
        US$532US$428

        Choose LATAM Airlines flights from Santiago to Lyon. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Mon, Nov 18, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$428 including taxes and charges.

      • SCL00:30
        19h 15m
        1 stop
        LYS23:45
        Sat, Dec 14|Santiago - Lyon|LATAM Airlines
        US$438US$532
        18% OFF
        18% OFF
        US$532US$438

        Choose LATAM Airlines flights from Santiago to Lyon. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Sat, Dec 14, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$438 including taxes and charges.

      • SCL16:00
        20h
        1 stop
        LYS16:00
        Sun, Dec 1|Santiago - Lyon|LATAM Airlines
        US$451US$532
        15% OFF
        15% OFF
        US$532US$451

        Choose LATAM Airlines flights from Santiago to Lyon. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Sun, Dec 1, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$451 including taxes and charges.

      • SCL13:10
        18h 45m
        1 stop
        LYS11:55
        Tue, Nov 26|Santiago - Lyon|Iberia
        US$458
        US$458

        Choose Iberia flights from Santiago to Lyon. The one-way connecting flight with Iberia departs from Arturo Merino Benitez Airport on Tue, Nov 26, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$458 including taxes and charges.

      • SCL13:10
        18h 45m
        1 stop
        LYS11:55
        Mon, Nov 18|Santiago - Lyon|Iberia
        US$459
        US$459

        Choose Iberia flights from Santiago to Lyon. The one-way connecting flight with Iberia departs from Arturo Merino Benitez Airport on Mon, Nov 18, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$459 including taxes and charges.

      • SCL00:30
        15h 50m
        1 stop
        LYS20:20
        Tue, Dec 3|Santiago - Lyon|Iberia
        US$465
        US$465

        Choose Iberia flights from Santiago to Lyon. The one-way connecting flight with Iberia departs from Arturo Merino Benitez Airport on Tue, Dec 3, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$465 including taxes and charges.

      • SCL00:30
        15h 50m
        1 stop
        LYS20:20
        Sat, Nov 16|Santiago - Lyon|Iberia
        US$467
        US$467

        Choose Iberia flights from Santiago to Lyon. The one-way connecting flight with Iberia departs from Arturo Merino Benitez Airport on Sat, Nov 16, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$467 including taxes and charges.

      • SCL13:10
        18h 45m
        1 stop
        LYS11:55
        Wed, Nov 27|Santiago - Lyon|Iberia
        US$467
        US$467

        Choose Iberia flights from Santiago to Lyon. The one-way connecting flight with Iberia departs from Arturo Merino Benitez Airport on Wed, Nov 27, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$467 including taxes and charges.

      • SCL13:10
        18h 45m
        1 stop
        LYS11:55
        Sun, Dec 1|Santiago - Lyon|Iberia
        US$473
        US$473

        Choose Iberia flights from Santiago to Lyon. The one-way connecting flight with Iberia departs from Arturo Merino Benitez Airport on Sun, Dec 1, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$473 including taxes and charges.

      • SCL21:05
        19h 15m
        1 stop
        LYS20:20
        Tue, Nov 19|Santiago - Lyon|LATAM Airlines
        US$473
        US$473

        Choose LATAM Airlines flights from Santiago to Lyon. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Tue, Nov 19, arriving at Lyon Saint-Exupery Airport. One-way ticket prices start from US$473 including taxes and charges.

      • SCL13:00
        3h 5m
        Nonstop
        LYS14:00
        Sat, Nov 23|Santiago - Lyon|LATAM Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Find the best time to fly from Santiago to Lyon

Explore the best time to buy affordable tickets to Lyon with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Airlines Flying from Santiago to Lyon

Which airline provides the cheapest flights from Santiago to Lyon? Discover the option that best suits your travel needs before embarking on your journey.

LATAM Airlines
From US$403
Iberia
From US$431
avianca
From US$489
Vueling Airlines
From US$527
Air Canada
From US$618
JetSMART
From US$623
Sky Airline
From US$655
United Airlines
From US$658
British Airways
From US$667
Aerolineas Argentinas
From US$708

Find more flights and airlines

Alternative Routes from Santiago to Lyon

There are various non-direct routes from Santiago to Lyon which could be cheaper and faster! Check out these alternative options to see if they could work for your trip.

  • Cheapest
    LATAM Airlines
    SCL
    09:05
    33h 45m
    2 transfer
    LYS
    22:50
    Arturo Merino Benitez Airport - Lyon Saint-Exupery Airport
    Thu, Nov 28LATAM Airlines
    US$403
  • avianca
    SCL
    15:25
    38h 50m
    2 transfer
    GNB
    10:15
    Arturo Merino Benitez Airport - Grenoble Airport
    Mon, Dec 2avianca
    US$489
  • avianca
    SCL
    15:25
    38h 50m
    2 transfer
    GNB
    10:15
    Arturo Merino Benitez Airport - Grenoble Airport
    Mon, Dec 2avianca
    US$489
    Find More Flights

FAQ

  • When are flight tickets from Santiago (SCL) to Lyon (LYS) the cheapest?

    Airlines adjust prices for flights from Santiago to Lyon based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Santiago (SCL) to Lyon (LYS) cost?

    According to Trip.com's data, the lowest price is around $1,160.

  • What is the transportation method from the main airport to downtown in Lyon?

    • The distance from Lyon Saint-Exupery Airport to downtown is about 19 km. It takes about 30 minutes by taxi.
    • The distance from Grenoble Airport to downtown is about 59 km. It takes about 1 hour 10 minutes by taxi.

How to find a cheap flight from Santiago to Lyon

If you leave it until the last minute and forget to check some of the key information when booking tickets, prices can often end up skyrocketing. Below, you can find our top tips for getting the best value flights – from changing dates to chasing deals, there are plenty ways to keep your next trip affordable.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Santiago to Lyon

Cheapest nonstop flight price$427
Off-season for travelDecember
Peak season for travelAugust
Flight distance11,619.81 km
Popular airlineAir France

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