Hotels in Seneca

Search Best Hotels in Seneca

Enter your dates for the latest hotel rates and availability.

Scroll down to see hotels
Filter by:
Hotel Star Rating
≤2345
Guest Rating
Amazing 9+Great 8+Good 7+Pleasant 6+
Popular Filters for Seneca
1 king bedWithin 1 kmMotelGood 7+Free cancellationEntire unitBest WesternSuiteBreakfast includedSmoking room
Property Type
HotelMotel
Property facilities & services
Wi-Fi in public areas24-hour front deskParking availableFree parkingPoolEV charging stationGymElevatorPets welcomeLuggage storageWake-up callSmoking areaConference room

6 hotels in Seneca for your stay

Choose your travel dates to see the latest prices and deals.
Most Booked
Lowest price
Closest to downtown
Highest Rated
Best Western Seneca-Clemson Hotels in Seneca
Best Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in Seneca
44
Hotels in Seneca
Public parking
Wake-up call
Wi-Fi in public areas
+2
"My experience will gyood. The front desk clerk is very kind."
Very Good
102 reviews
8.3/10
1 night
From PLN 343
Check Availability
Days Inn by Wyndham Seneca / Clemson Area Hotels in Seneca
Days Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in Seneca
32
Hotels in Seneca
Private parking
EV charging station
Gym
+2
"It was ok, not bad. Would stay again definitely. Could work on amenities. No conditioner toothpaste. But overall it was a pleasure to have stayed"
96 reviews
6.9/10
1 night
From PLN 245
Check Availability
Fairfield Inn & Suites Seneca Clemson Univ Area Hotels in Seneca
Fairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in Seneca
65
Hotels in Seneca
Gym
Wi-Fi in public areas
"Very clean, the surrounding environment is also very beautiful, there is also breakfast, a very cost-effective hotel"
Great
78 reviews
9.0/10
1 night
From PLN 496
Check Availability
Quality Inn Seneca US-123 Hotels in Seneca
Quality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in Seneca
72
Hotels in Seneca
Private parking
EV charging station
Wi-Fi in public areas
+3
"Room was clean and the bed linens smelled fresh. The front office staff and maids were all amiable and happy to be helpful. Breakfast was carb city. Did have self made hot waffles, muffins, cereals, yogurt bananas and coffee n juice. We stayed three nights and would be happy to go back."
Good
95 reviews
7.9/10
1 night
From PLN 285
Check Availability
Hampton Inn & Suites Seneca-Clemson Area Hotels in Seneca
Hampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in Seneca
99+
Hotels in Seneca
Public parking
EV charging station
Gym
+7
Welcome to the Hampton Inn & Suites Seneca-Clemson Area, a warm and welcoming hotel just a short distance from Lake Keowee and downtown Seneca, SC. Enjoy easy access to local restaurants, state parks, lakes and leisure amenities including golf. Popular Seneca attractions including the Blue Ridge Mountains, the World of Energy and Clemson University are all close to our relaxed hotel in Seneca, SC. Settle in to a beautifully decorated guest room or suite, where you can stay connected with free WiFi at the ergonomic desk, watch the satellite TV and get a great night's sleep on the clean and fresh Hampton bed. Other great amenities include an in-room microwave and refrigerator and guest laundry facilities are available at this Seneca hotel. Every morning, enjoy Hampton's free hot breakfast buffet, offering everything from light continental favorites to hot items and buy snacks at any time from the 24-hour Suite Shop. Enjoy free tea and coffee in the modern lobby, 24-hours a day and ask our friendly staff for advice on what to see and do during your stay. Stay connected with the free business center or hold a meeting in the 600 sq.ft. conference room. Energize in the free fitness center, swim in the outdoor, saltwater pool or relax under an umbrella on the poolside patio area. Friendly service, clean rooms, comfortable surroundings, every time. If you're not satisfied, we don't expect you to pay. That's our commitment and your guarantee. That's 100% Hampton.
Great
95 reviews
9.2/10
1 night
From PLN 423
Check Availability
The Big Golf House- 10 miles to Clemson Hotels in Seneca
The Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in Seneca
26
Hotels in Seneca
Wi-Fi in public areas
Welcome to your spacious golf course retreat in Seneca, South Carolina, just 15 minutes from Clemson University and minutes from Lake Keowee. This 4,700 sq ft, 4-bedroom, 4-bathroom home is perfect for Clemson football weekends, family gatherings, or lake getaways.Inside, you’ll find room for everyone with multiple living areas, large bedrooms, and four bathrooms. Entertainment is built in with a game room, bar, and private arcade, making the house just as fun to enjoy as the surrounding area. Start your mornings with coffee overlooking the course, and spend your evenings relaxing with family and friends in a private, peaceful setting.Guests love the quiet golf course atmosphere while still being close to everything: Lake Keowee marinas and boat rentals, hiking trails, local dining in downtown Seneca, and Clemson’s stadium.Whether you’re here for game day excitement, a lake adventure, or simply to unwind in a luxury vacation rental, this home combines space, comfort, and location in a way that makes every stay unforgettable.Note:Your safety matters. This property features a Ring doorbell device and flood light that have an exterior security camera facing the front outdoor entry. The camera does not look into any interior spaces. The camera actively records video when motion is detected by the deviceAbout pets:Pets allowed: dogs (limit 2 total).About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
Check Availability
See all hotels in Seneca

Trip.com's insights for hotels in Seneca

Plan smarter with Trip.com’s data-backed insights on travel seasons so that you can book your Seneca hotel at the right time!

What is the cheapest day of the week for hotels in Seneca?

Hotel rates in Seneca are typically lowest on Wednesday, with average nightly rates around PLN 339. Monday tends to be the most expensive, averaging PLN 652 per night.
(Based on Trip.com data from March 17, 2025 to March 17, 2026.)
Mon
Tue
Wed
Thu
Fri
Sat
Sun

Explore accommodation types in Seneca

Immerse yourself in the vibrant atmosphere of Seneca with our handpicked accommodation options

FAQs About Hotels in Seneca

What hotel deals are available in Seneca?

Trip.com offers various events and deals to its users all year round. You can check the deals page to view Trip.com deals.

Which hotels in Seneca have swimming pools?

Which hotels in Seneca offer free WiFi?

Whether you are travelling for business or vacation, an internet connection is a must for your trip. Fairfield Inn & Suites Seneca Clemson Univ Area (from PLN 495), Best Western Seneca-Clemson (from PLN 389) and Days Inn by Wyndham Seneca / Clemson Area (from PLN 252) are popular hotels with free Wi-Fi.

Which hotels in Seneca have fitness facilities?

Which hotels in Seneca provide high-quality breakfasts?

What is the average hotel price in Seneca?

For hotels in Seneca, the average price on weekdays is PLN 529, the average price on weekends (Friday–Saturday) is PLN 700.

What are the most popular hotels in Seneca?

Seneca has many popular hotels. Whether you're traveling for business or going on a vacation, Fairfield Inn & Suites Seneca Clemson Univ Area (from PLN 495), Best Western Seneca-Clemson (from PLN 389) and Days Inn by Wyndham Seneca / Clemson Area (from PLN 252) are preferred hotels.

Hotel Information for Tourists

Number of Reviews
466
Total Properties
6
Weekday Avg. Price
PLN 529
Weekend Avg. Price
PLN 700
Trending hotel
Fairfield Inn & Suites Seneca Clemson Univ Area